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Table 1 Summary of Survey Results

From: Attitudes of undergraduate medical students towards end-of-life decisions: a systematic review of influencing factors

Reference

Type of practice1

Country

Year of study

Study design

Age range (mean;SD)

Female/Male

Response Rate

Sample Size

Type of predictors investigated (* = sign.)

Intervention

Study Outcome

consent to palliative sedation

consent to (physician-)assisted suicide

consent to withdrawal of active therapy (PE/TW)

consent to active euthanasia

consent to euthanasia

consent to legalisation of EUT/PAS/AE

[41]

EUT

Hong Kong

2021

cross-sectional survey, anonymous online self-administered 28-item questionnaire

17–25

57.0%/43.0%

N/A

228

Age

Comparison of two universities

Ethnicity

Gender*

Religion*

Year of study

none

Association between attitudes and knowledge

Attitudes towards EUT

Exposure to EUT

Knowledge towards EUT

Readiness to assist decision-making on EUT

-

-

-

-

41.2%

-

[53]

EUT

PAS

Poland

N/A

cross-sectional survey, 18-item questionnaire

21–41 (24.71 ± 1.81)

59.26%/40.79%

94.1%

659

Place of residence*

none

Access to palliative care/pain therapy decreases EUT

Active participation in EUT/PAS

Attitudes towards legalisation

Claiming EUT/PAS for oneself

Ethical context

Knowledge about EUT/PAS

Personal arguments for claiming EUT/PAS for oneself

Personal arguments for practicing EUT

Risk of abuse

Teaching Palliative Care

Values in contact with patients

-

-

-

-

25.9%

34.4% (EUT)

[64]

PAS

Germany

2020

cross-sectional study, self-administered 10-item questionnaire

mean 24.5 (± 3.5)

62%/38%

82%

271

(4th year)

N/A

none

Active participating in PAS

Attitudes towards PAS

Claiming PAS for oneself

Teaching PAS

Knowledge regarding legislation

-

93%

-

-

-

-

[44]

AE

EUT

PAS

India

2020

cross-sectional survey, self-administered questionnaire

N/A

61.5%/38.5%

N/A

400 (1st, 2nd, 3rd and final year)

Gender

none

Attitude towards EUT/PAS

Knowledge towards EUT

Legalisation of EUT/AE

Person controlling EUT/Person deciding over EUT

Reasons to support/oppose EUT

Risk of abuse

-

38%

-

-

72%

61% (AE)

75% (PE)

[49]

PAS

New Zealand

2018

mixed-methods online survey

18–40

61.8%/38.2%

28%

326 (2nd to 5th year)

Ethnicity

Gender

Religiosity*

Year of study*

none

Attitudes towards legalisation of PAS

-

-

-

-

-

56% (AE)

[52]

AE

Serbia

2017

cross-sectional survey, paper-based 10-item questionnaire

N/A

N/A

N/A

107

N/A

none

Acceptance/refusal of AE in hypothetical scenarios

Attitudes towards AE

Claiming AE for oneself

Ethical acceptance of AE

Legalisation of AE

Personal arguments for claiming AE

-

-

-

57%

-

44% (AE)

[37]

AE

PAS

PE

Turkey

2018

-

2019

cross-sectional survey, paper-based 11-item questionnaire

18–40

57.9%/42.1%

78.9%

242

(1st & 6th year)

Gender

Year of study*

none

Active participating in EUT

Arguments in favour/against EUT

Attitudes towards AE/PAS/PE

Ethical justification of EUT

Legalisation of EUT

Risk of abuse

-

28.9%

27.3% (PE)

35.9%

-

33.4% (EUT)

[43]

AE

EUT

PE

Iran

2016

cross-sectional study, self-administered questionnaire

18–28 (mean 22.12 ± 2.35)

60.5%/39.5%

N/A

152

Age*

Gender

Year of study*

none

Active participating in EUT

Attitudes towards AE/PE

-

-

44.7% (PE)

30.9%

-

-

[42]

EUT

India

N/A

cross-sectional study, semi-structured 10-item questionnaire

N/A

N/A

N/A

96

N/A

none

Attitudes towards EUT

Current legislation on EUT

Knowledge about EUT

Legalisation on EUT

-

-

-

-

41.7%

83.3% (EUT)

[30]

PAS

Canada

2016

-

2017

cross-sectional survey, self-administered, anonymous online 47-item questionnaire

18–30 + 

N/A

12%

1210

Age

Birthplace*

Frequency of religious attendance*

Gender

Parental education

Educational background

Province of Canada*

Religion*

Urban/rural upbringing

Year of study

none

Active participating in PAS

-

71%

-

-

-

-

[59]

AE

TW

PS

UK

N/A

cohort study, paper-based, self-completion questionnaire with 5 scenarios

18–44 (mean 22.7)

59.8%/

40.2%

79%

400

(1st and final year)

Age*

Gender

Graduate status*

Personal belief*

Religious background*

Year of study*

none

Active participation in AE

Attitudes towards AE/TW/PS

-

28%

58%

16%

-

-

[47]

EUT

PAS

South Africa

2016

-

2017

semi-quantitative survey, modified [57] paper-based 16-item questionnaire

N/A

N/A

69.3%

277

(3rd, 4th and 5th year)

Religion

none

Acceptance/refusal of EUT/PAS in hypothetical scenarios

Active participating in EUT/PAS

Attitudes towards EUT/PAS

Personal arguments in favour and against EUT/PAS

-

35%

-

-

47.7%

52.7% (EUT/PAS)

[29]

AE

PE

Mexico

N/A

cross-sectional survey, modified [34, 77] 9-item questionnaire

17–30

54.7%/43.3%

N/A

1319

Age

Gender*

Importance of religiosity and spirituality*

Religion*

Year of Study

none

Arguments in favour/against AE/PE

Attitudes towards PE/AE

Claiming AE for oneself

Legalisation of AE/PE

-

-

52.1% (PE)

44.4%

-

-

[38]

EUT2

Turkey

2017

cross-sectional survey, 13-item online questionnaire

N/A

N/A

N/A

125

N/A

none

Arguments in favour/against EUT

Attitudes towards (paediatric) EUT

Conditions under which paediatric EUT is acceptable

Level of agreement with legalisation

Person controlling EUT/Person deciding over EUT

Risk of abuse

-

-

-

-

32%

-

[48]

EUT

PAS

TW

South Africa

2016

cross-sectional study, adapted [78] 12-item questionnaire

17–25

58.7%/41.3%

71.6%

481

Comparison of preclinical (1st and 2nd year) vs. clinical (3rd, 4th and 5th year) students

none

Active participating in PAS

Attitudes towards EUT/PAS

Claiming PAS for oneself

Legalisation of PAS

Person controlling PAS/Person deciding over PAS

-

36.2%

69.8%

-

30.1%

43.0% (AS)

[28]

AE EUT PAS

Canada

2015

exploratory cross-sectional survey, self-administered, 16-item questionnaire

N/A

57.3%/42.7%

87.1%

405

Gender

Spirituality

Year of study

none

Acceptance/refusal of EUT/PAS in hypothetical scenarios

Active participating in PAS/AE

Arguments in favour/against PAS

Legalisation of PAS

Person controlling/practicing PAS

-

61%

-

38%

-

88% (AS)

[50]

EUT PAS PE

Germany

N/A

case vignette study

mean 24 (± 2.8)

68.5%/31.5%

80%

241

(4th year)

Age

Gender

none

Assumed permissibility for PS/PAS/AE

Attitudes towards PS/PAS/AE

Comparison physical vs. emotional suffering

Ethical acceptability of PS/PAS/AE

Knowledge about legal norms

Rates of consent to different types of practice

83.8%

51.2%

-

-

19.2%

-

[60]

EUT

PS

Belgium

2012

cross-sectional study, self-administered 22-item questionnaire

N/A

N/A

45.1%

335

Gender

Philosophy of life*

none

Arguments accepting/supporting EUT

Attitudes towards EUT

Attitudes towards EUT law

Claiming EUT/PS for oneself

Knowledge about EUT/PS

Personal experience with EUT/PS

-

-

-

-

31.8%

95.9% (EUT)

[58]

EUT

PAS

Norway

2012

cross-sectional study, paper-based questionnaire

N/A

65.5%/34.5%

59%

531 (5th and 6th year)

Gender

Religion

none

Active participating in EUT

Attitudes towards EUT/PAS

Legalisation of EUT/PAS

-

-

-

-

-

19.4% (EUT)

31.2% (PAS)

[32]

EUT

TW

Brazil

2010

-

2011

cross-sectional survey, adapted [79,80,81] 43-item questionnaire

mean 22.5 (± 4.6)

53.8%/46.2%

61.0%

3630

Age

Believe in soul*

Gender

Income*

Location of the university (urban vs. rural)*

Number of medical students*

Religion*

Religious affiliation*

Religious attendance*

Year of school foundation*

none

Attitude towards EUT/TW

-

-

45.7%

-

41.4%

-

[34]

AE

PAS

TW

Mexico

2007

cross-sectional survey, adapted [77] 9-item questionnaire

18–25

54%/46%

N/A

99 (3rd and 4th year)

Age

Comparison of religiously and lay-administered medical schools*

Gender

Importance of religion

Religion

none

Acceptance/refusal of PAS in hypothetical scenarios

Attitudes towards AE/PAS/TW

Claiming PAS for oneself

Legalisation of PAS

-

52%

61%

-

-

-

[56]

EUT

PAS

Poland

2008

-

2009

cross-sectional survey intervention study, anonymous self-administered 12-item questionnaire

mean 24.44 (± 1.13)

67.35%/32.65%

90.5%

588 (5th and 6th year)

Age

Comparison of 2 universities*

Gender*

Intervention

Place of residence

Religion*

palliative medicine course with symptom management, psychological, social and spiritual support

Attitudes towards EUT/PAS

Attitudes towards EUT/PAS law

Claiming EUT/PAS for family member or friends

Claiming EUT/PAS for oneself

Knowledge towards EUT/PAS

Legalisation of EUT

Personal arguments in favour EUT practice

Risk of abuse

-

-

-

-

11.7%

29.6% (EUT/AS)

[57]

EUT

PAS

Poland

2001

-

2002

cross-sectional survey, anonymous 13-item questionnaire

mean 23.1 (± 2.2)

72%/28%

N/A

401

(3rd year)

Comparison of physicians and medical students*

none

Active participating in EUT

Attitudes towards EUT

Claiming EUT/PAS for family member or friends

Claiming EUT/PAS for oneself

Legalisation of EUT/PAS

Personal definitions of EUT

-

12%

-

-

12%

26% (EUT)

[55]

EUT

PAS

Poland

N/A

cross-sectional intervention study, anonymous 28-item questionnaire

N/A

32.8%/67.2%

N/A

320 (final year)

Comparison of medical and nursing students*

Effect of training program*

Effect of pilot training program within paediatric-palliative care (PPC)

Attitudes towards EUT

Evaluation of satisfaction from educational program

Knowledge towards PPC

Legalisation of EUT

Opinions on special problems of EUT

-

-

-

-

11.5% (BI)

9.5% (AI)

2.5% (BF)

3.5% (AF)

[40]

AE

EUT

Pakistan

2011

-

2012

cross-sectional survey, modified [82, 83] questionnaire

N/A

"3:1"

N/A

493

Comparison of two universities (private and public)

Gender*

Religion*

Year of study*

none

Active participation in EUT

Attitude towards AE

Knowledge about EUT

Legalisation of AE/EUT

-

-

-

32.9%

-

27% (EUT)

[63]

AE

Austria

2001 (I)

2003/04 (II)

2008/09 (III)

repetitive cross-sectional study, questionnaire

25.4 (I)

25.6 (II)

27.5 (III)

60.8%/39.2% (I)

62.2%/37.8% (II)

63.6%/36.4% (III)

91.7%

694

Survey phases*

none

Active participation in AE

Attitude towards AE

Personal motivation regarding acceptance/objection

-

-

-

30.8%

-

-

[54]

EUT

PAS

TW

PS

Greece

N/A

cross-sectional survey, self-administered, anonymous paper-based 20-item questionnaire

mean 24.7 (± 1.8)

44.6%/55.4%

94.4%

251

(final year)

Gender*

none

Attitudes towards EUT/PAS/TW/PS

Claiming PAS for family member or friends

Claiming PAS for oneself

Factors influencing attitudes towards PAS

Factors influencing deciding EUT/PAS

Legalisation of EUT/PAS

Request for PAS is evidence of a mental disorder

Requirements to be fulfilled for PAS

Risk for medical practice

53.3%

69.7%

79.2%

-

52.0%

-

[39]

AE

TW

China

N/A

cross-sectional survey, online & paper based, modified [84] 19-item questionnaire

mean 21.2 (SD 1.0)

61.2%/37.8%

62.9%

312

(1st, 2nd, 3th and 5th year)

Comparison medical vs. non-medical students

Gender

Religion

Year of study*

none

Acceptance/refusal of AE/TW in hypothetical scenarios

Attitudes towards AE/TW

Participants deciding over AE/TW

Person controlling EUT

-

-

56%

44%

-

-

[51]

AE PAS PE

PS

Germany

N/A

cross-sectional survey, anonymous mail survey, self-administered 13-item questionnaire

22–31 (25.0 ± 2.4)

69.9%/30.1%

25%

113

(2nd & 6th year)

Age

Comparison of two universities

Gender

Religion

Year of study*

none

Access to palliative care/pain therapy decreases AE

Active participation in EA

Anxiety in caring for non-curable patients

Arguments for claiming AE

Arguments for practicing AE

Attitudes towards AE

Claiming AE for oneself

Knowledge about AE/PAS/PE/PS

Knowledge about legal norms AE/PAS/PE/PS

Legalisation of AE

Medical education is preparation for carrying the dying

Risk of abuse

-

-

-

29.2%

-

32.7% (AE)

[62]

EUT

PAS

TW

Croatia

2003

/

2004

cross-sectional intervention study, 20-item questionnaire

mean 19

61%/39%

97% (2003)

93% (2004)

115 (1st year)

Age

Gender

High school education

Influence of educational course*

Parental education

Religious belief*

Residence*

Medical ethics and Bioethics course: lectures with religious and cultural aspects of dying, sociology of death, definitions and classification of death and dying, and hospice and palliative care

Attitudes towards EUT/PAS/TW

Legalisation of EUT/AE

-

85.2%

83.5%

-

-

80% (EUT)

[61]

PAS

Germany

2002

-

2003

cross-sectional study, self-administered, paper-based questionnaire

mean 25.5

60.0%/37.6%

83.3%

85 (5th year)

Age

Gender

Religion

none

Claiming PAS for oneself

Ethical perspectives on PAS

Knowledge about PAS

Legalisation of PAS

Personal experience with PAS

-

24.7%

-

-

-

36.5% (AS)

[33]

EUT

PAS

PS

Puerto Rico

2004

cross-sectional study, self-administered, paper-based 17-item questionnaire

N/A

N/A

N/A

152

Comparison between students, residents and members of medical faculties*

Gender*

Religious affiliation

none

Active participation/engagement in PAS

Attitudes towards PAS/EUT

Legalisation of PAS

Oppose engaging others in PAS

76.3%

13.2%

-

-

27.6%

46.1% (PAS)

[69]

EUT

Poland

N/A

cross-sectional, self-administered 5-item questionnaire

N/A

N/A

N/A

50

Comparison of medical students, law students and general public

none

Acceptance/refusal of EUT

Active participation in EUT

Attitudes towards EUT law

Claiming EUT for family member

Claiming EUT for oneself

-

-

-

-

36%

-

[68]

AE

EUT

PAS

Switzerland

2005

cross-sectional study, anonymous questionnaire

N/A

N/A

100%

140 (1st and 2nd year)

Comparison of oncology clinicians, palliative care specialists and medical students

none

Active participating in AE/PAS

Attitudes towards AE/EUT/PAS

Claiming AE/PAS for oneself

Legalisation of AE/PAS

Person controlling EUT/Person deciding over EUT

-

64%

-

55%

-

70% (AE)

77% (PAS)

[46]

EUT

Sudan

2002

cross-sectional survey, paper-based questionnaire

23–27

43.5%/58.6%

83.5%

152

(final year)

Gender

Religiosity

none

Active participation in EUT

Arguments in favour and against EUT

Attitude towards EUT

Ethical justification of EUT

Knowledge about EUT

Legalisation of EUT

Teaching EUT

-

-

-

-

23.4%

23.4% (EUT)

[31]

PAS

Canada

2004

cross-sectional survey, paper-based, 13-item questionnaire

20–29 + 

56.2%/43.8%

53%

124

(1st & 4th year)

Age

Gender*

Year of study*

none

Active participation in PAS

Attitudes towards PAS

Claiming PAS for oneself

Factors influencing decision-making regarding PAS

Level of agreement with legalisation

-

37%

-

-

-

39% (PAS)

[36]

AE

EUT

PE

Malaysia

1998

-

1999

cross-sectional design, self-administered 12-items questionnaire

N/A

N/A

100%

400

Comparison of pre-clinical vs. clinical students

Ethnic background

none

Active participating in EUT

Arguments in favour and against PE/AE

Attitudes towards PS/AE

Claiming EUT for oneself

Knowledge about EUT

Legalisation of EUT

Person controlling EUT

Reasons against PE/AE

Risk of abuse

-

-

52% (PE)

27%

-

33% (EUT)

[71]

EUT

AS

Poland

N/A

cross-sectional survey, anonymous online self-administered 22-item questionnaire

19–33 (22.49 ± 2.56)

68.5%/30.6%

N/A

108 (1st to 4th year)

Age

Gender

Religion*

Place of residence

none

Attitudes towards EUT/AS

Claiming EUT/AS for oneself

Knowledge about EUT/AS

Knowledge about EUT/AS

Legalisation of EUT/AS

Personal experience

Readiness to assist decision-making on EUT/AS

-

-

-

-

 

68.7% (EUT)

38% (AS)

[72]

PAS

Ireland

2023

cross-sectional survey, online 13-item questionnaire

18–26 + 

62%/37%

20.9%

200

Gender*

Religion

Year of study

none

Acceptance/refusal of PAS

Attitude towards PAS

Arguments in favour and against PAS

Attitude towards legalisation

Factors influencing attitudes towards PAS

Teaching PAS

Personal arguments in favour and against

Readiness to assist in decision-making on PAS

-

59.5%

-

-

-

-

[74]

EUT

Poland

2018

cross-sectional survey, anonymous 35-item questionnaire

18–24

65.5%/34.5%

77.6%

281 1st year

Age

Gender

Grandparents living with the family

Number of siblings*

Place of residence

Religious engagement*

None

Attitude towards EUTS

Attitude towards legalisation

Risk of abuse

-

-

-

-

18.2%

27.6% (EUT)

[73]

EUT

Poland

N/A

cross-sectional survey, anonymous 35-item questionnaire

N/A

N/A

N/A

280

Comparison of psychology, economic-technical and medical students*

None

Attitude towards EUT

Acceptance/Refusal of EUT

Risk of abuse

-

-

-

-

18.2%

-

[45]

EUT

PAS

Pakistan

2023

cross-sectional survey

17–26

N/A

N/A

316

Religion*

Gender

Year of study*

None

Attitude towards EUT/PAS

Attitudes towards legalisation

Risk of abuse

-

21.5%

-

-

19.2%

-

[75]

EUT

Serbia

2017

cross-sectional survey, 10-item questionnaire

N/A

64.4%/

35.4%

94.4%

97.6%

551 (2nd & 5th year)

Comparison of two universities

Gender

Parental education level

Socio-economic status

Year of study

None

Attitude towards EUT

Attitude towards legalisation

Person deciding over EUT

Risk of abuse

-

-

-

-

-

57.9% (EUT)

[76]

AS

Germany

2021—2022

online evaluation

N/A

N/A

66.1%

37

N/A

Elective course on AS in palliative care with theoretical knowledge and practical simulations with standardised patients to improve communication, knowledge and compassionate care

Attitude towards AS

Teaching palliative Care

-

68%

-

-

-

-

  1. 1Type of end-of-life practice: AE: active euthanasia; PAS: physician assisted suicide; PS: palliative sedation; PE: passive euthanasia; TW: treatment withdrawal/withholding
  2. 2on pediatric patients
  3. *were significant factors in the respective study